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Wait . . . Trump& #39;s big presser coronavirus "breakthrough" was plasma therapy?
Seriously??
Like they were doing in April? https://www.pnas.org/content/117/17/9490">https://www.pnas.org/content/1...
Seriously??
Like they were doing in April? https://www.pnas.org/content/117/17/9490">https://www.pnas.org/content/1...
Let& #39;s see what th . . . oh. "The decision to issue an emergency use authorization, which President Trump’s press secretary heralded ahead of time as a & #39;major therapeutic breakthrough,& #39; likely falls far short of that description." https://www.statnews.com/2020/08/23/fda-under-pressure-from-trump-expected-to-authorize-blood-plasma-as-covid-19-treatment/">https://www.statnews.com/2020/08/2...
An FDA staffer who reviewed the data on convalescent plasma — and whose name was redacted from a memo released by the agency — was far less enthusiastic, writing that the data . . . (cont)
(cont.) . . . “support the conclusion that [convalescent plasma] to treat hospitalized patients with COVID-19 meets the ‘may be effective’ criteria for issuance of an EUA. "
MAY be. So that 35% effectiveness in use that isn& #39;t from proper clinical trials is what? A big maybe.
MAY be. So that 35% effectiveness in use that isn& #39;t from proper clinical trials is what? A big maybe.
That& #39;s because 35% of the people who got plasma therapy didn& #39;t die.
So 65% who did get plasma therapy did die.
And since these weren& #39;t randomized clinical trials, no one can say for certain what, if any, effect the plasma therapy had.
Marvy.
So 65% who did get plasma therapy did die.
And since these weren& #39;t randomized clinical trials, no one can say for certain what, if any, effect the plasma therapy had.
Marvy.
Back to the FDA staffer, "Adequate and well-controlled randomized trials remain nonetheless necessary for a definitive demonstration of … efficacy and to determine the optimal product attributes and the appropriate patient populations for its use.”
Plasma therapy for treatment of COVID-19 is not new, but it& #39;s also not proven. Here& #39;s a breakdown of that in this thread: https://twitter.com/EricTopol/status/1297583093285494785">https://twitter.com/EricTopol...
