First up: Oxford scientists publish their first clinical trial paper on their chimp adenovirus vaccine, to be made by Astra Zeneca. Phase I/II trial indicates it’s safe (lots of mild side effects), produces some antibodies, some interferon. 2/9
CanSinoBio has its own paper out in the Lancet, demonstrating an immune response to a vaccine based on another adenovirus, Ad5 3/9
BioNTech & Pfizer report more Phase I/II data in a preprint, showing immune response to the coronavirus to their mRNA vaccine 4/9
Kentucky BioProcessing has registered a Phase I trial for a protein-based vaccine made by a species of tobacco plant. It’s the second company linked to a cigarette maker to enter the race. (Medicago is the other.) 5/9
North Korea announced its own Phase I trial of a coronavirus vaccine, but it’s hard to know what to make of that—no preclinical data on offer, and an assertion that they& #39;ll have to test the vaccine outside of North Korea because the country has ZERO cases of #covid19 https://abs.twimg.com/emoji/v2/... draggable="false" alt="🙄" title="Gesicht mit rollenden Augen" aria-label="Emoji: Gesicht mit rollenden Augen"> 7/9
All in all, quite a morning. But it’s vital to remember: NO VACCINE HAS YET BEEN PROVEN EFFECTIVE AT PREVENTING #COVID19. Advances and reports are encouraging, but scientists have yet to show that the immune responses they’re seeing are enough to fend off the coronavirus. 8/9
But if everything goes right we may not have to wait long for the first results of effectiveness trials. Anyway—check out the whole shebang here: https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html">https://www.nytimes.com/interacti... 9/9
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