1. This Thread will attempt to gather information on the potential treatment of Quercetin and Zinc against COVID-19. I will try to include various studies,articles,anecdotal evidence to help establish a case for its potential anti-viral effects especially when taken early on.
3. Study receives 1 million dollar donation to initiate trials in China: https://ircm.qc.ca/en/news/lazaridis-family-foundation-contributes-1-million-ircm-support-its-research-covid-19">https://ircm.qc.ca/en/news/l...
5. Radio interview with the leading researchers, Dr Michel Chrétien and Dr Majambu Mbikay: https://www.cbc.ca/player/play/1703914563515">https://www.cbc.ca/player/pl...
6. Video interview on CBC News: https://mobile.twitter.com/CBCNews/status/1233454888400670724">https://mobile.twitter.com/CBCNews/s...
9. I will now proceed to link various studies that deal with the benefits of Quercetin, especially it’s potential against diseases, bacteria and viruses.
10. Study of Quercetin efficacy against SARS- Severe acute respiratory syndrome coronavirus (SARS-CoV) is the pathogen of SARS, which caused a global panic in 2003: #T1">https://jvi.asm.org/content/78/20/11334 #T1">https://jvi.asm.org/content/7...
14. Study of Quercetin on Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer:
https://www.ncbi.nlm.nih.gov/pubmed/19149749 ">https://www.ncbi.nlm.nih.gov/pubmed/19...
15. Study on suppression of cancer cell growth and inducing cell death in Prostate cancer cells:
https://www.spandidos-publications.com/or/33/6/2659 ">https://www.spandidos-publications.com/or/33/6/2...
16. And this Study as well: https://www.ncbi.nlm.nih.gov/pubmed/32174789 ">https://www.ncbi.nlm.nih.gov/pubmed/32...
17. Here is other Quercetin anti-cancer research on test tube and animal studies on liver, lung, breast, bladder, blood, colon, ovarian, lymphoid, and adrenal cancer cells:
A. https://www.ncbi.nlm.nih.gov/pubmed/28677813 
B.">https://www.ncbi.nlm.nih.gov/pubmed/28... https://www.ncbi.nlm.nih.gov/pubmed/28264020 
C.">https://www.ncbi.nlm.nih.gov/pubmed/28... https://www.ncbi.nlm.nih.gov/pubmed/24223637 
D.">https://www.ncbi.nlm.nih.gov/pubmed/24... https://www.ncbi.nlm.nih.gov/pubmed/27186419 ">https://www.ncbi.nlm.nih.gov/pubmed/27...
18. Here are Studies of some positive effects of Quercetin on Alzheimer’s disease and Dementia:
A. https://www.ncbi.nlm.nih.gov/pubmed/26904161 
B.">https://www.ncbi.nlm.nih.gov/pubmed/26... https://www.ncbi.nlm.nih.gov/pubmed/25666032 
C.">https://www.ncbi.nlm.nih.gov/pubmed/25... https://www.ncbi.nlm.nih.gov/pubmed/29736217 ">https://www.ncbi.nlm.nih.gov/pubmed/29...
19. Here are some studies of the effects of Quercetin on High blood pressure:
A. https://www.ncbi.nlm.nih.gov/pubmed/12065701/
B.">https://www.ncbi.nlm.nih.gov/pubmed/12... https://www.ncbi.nlm.nih.gov/pubmed/8919657/ 
C.">https://www.ncbi.nlm.nih.gov/pubmed/89... https://www.ncbi.nlm.nih.gov/pubmed/11325801 
D.">https://www.ncbi.nlm.nih.gov/pubmed/11... https://www.ncbi.nlm.nih.gov/pubmed/27405810 ">https://www.ncbi.nlm.nih.gov/pubmed/27...
20. Studies on the effect of Quercetin on combatting aging:
A. https://www.ncbi.nlm.nih.gov/pubmed/28966753 
B.">https://www.ncbi.nlm.nih.gov/pubmed/28... https://www.ncbi.nlm.nih.gov/pubmed/29988130 
C.">https://www.ncbi.nlm.nih.gov/pubmed/29... https://www.ncbi.nlm.nih.gov/pubmed/29737207 ">https://www.ncbi.nlm.nih.gov/pubmed/29...
21. Studies on the effects of Quercetin to aid blood sugar levels in Diabetics:
A. https://www.ncbi.nlm.nih.gov/pubmed/30848564 
B.">https://www.ncbi.nlm.nih.gov/pubmed/30... https://www.ncbi.nlm.nih.gov/pubmed/30735748 
C.">https://www.ncbi.nlm.nih.gov/pubmed/30... https://www.ncbi.nlm.nih.gov/pubmed/30551359 ">https://www.ncbi.nlm.nih.gov/pubmed/30...
22. Here is a study on the anti-inflammatory properties of Quercetin. It is specifically important given the potential of inhibiting the high cytokine storm induced by Covid-19,causing major complications like pneumonia etc. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926454/">https://www.ncbi.nlm.nih.gov/pmc/artic...
24. In test-tube studies, quercetin reduced markers of inflammation in human cells, including the molecules tumor necrosis factor alpha (TNFα) and interleukin-6 (IL-6). Here are two studies with regard to that:
A. https://www.ncbi.nlm.nih.gov/pubmed/20943792 
B.">https://www.ncbi.nlm.nih.gov/pubmed/20... https://www.ncbi.nlm.nih.gov/pubmed/27294919 ">https://www.ncbi.nlm.nih.gov/pubmed/27...
25. An 8-week study in 50 women with rheumatoid arthritis observed that participants who took 500 mg of quercetin experienced significantly reduced early-morning stiffness, morning pain, and after-activity pain. They had reduced markers of inflammation: https://www.ncbi.nlm.nih.gov/pubmed/27710596 ">https://www.ncbi.nlm.nih.gov/pubmed/27...
26. Quercetin’s anti-inflammatory properties may provide allergy symptom relief. Studies found that it may block inflammatory enzymes and suppress inflammation-promoting chemicals, such as histamine.
A. https://www.ncbi.nlm.nih.gov/pubmed/27187333 
B.">https://www.ncbi.nlm.nih.gov/pubmed/27... https://www.ncbi.nlm.nih.gov/pubmed/18187018 
C.">https://www.ncbi.nlm.nih.gov/pubmed/18... https://www.ncbi.nlm.nih.gov/pubmed/21625024 ">https://www.ncbi.nlm.nih.gov/pubmed/21...
27. Another study showed that taking quercetin supplements suppressed peanut-related anaphylactic reactions in mice:
https://www.ncbi.nlm.nih.gov/pubmed/20548131 ">https://www.ncbi.nlm.nih.gov/pubmed/20...
29. Now let’s turn our attention to the possible effects of Quercetin on SARS-COV-2, otherwise known as COVID-19.
There are various ways Quercetin may be effective in inhibiting the effects of the coronavirus.
31. More detail: https://twitter.com/ne02012/status/1249760290113089539">https://twitter.com/ne02012/s...
32. Yet more detail on the mechanism of how Quercetin may block virus entry into cells. Here is the table from the Supercomputer simulation mentioned above: https://mobile.twitter.com/taitlog/status/1241859474781917184">https://mobile.twitter.com/taitlog/s...
33. This seems to be the mechanism proposed by the Montreal researchers mentioned above. Here is a piece of the article mentioned above: https://www.mcgilltribune.com/sci-tech/montreal-researchers-propose-a-treatment-for-covid-19-170320/">https://www.mcgilltribune.com/sci-tech/...
35. This is essentially the same process behind chloroquine/Hydroxychloroquine as they are both Zinc Ionophores. This is one of the leading theories behind their efficacy as anti-viral drugs. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182877/">https://www.ncbi.nlm.nih.gov/pmc/artic...
36. Here is a great video demonstrating how chloroquine/Hydroxychloroquine work as zinc ionophores to inhibit virus replication: https://m.youtube.com/watch?v=BIymfznD7YA">https://m.youtube.com/watch...
37. As an aside I would like to share two recent documents showing the strong efficacy of Hydroxychloroquine and Zinc in fighting Covid-19.
A) https://docs.google.com/document/u/0/d/1ka76CL50hR_a0b5oIhEAVY4gfyqkJcBxXBcP0r2nrz0/mobilebasic">https://docs.google.com/document/...
39. Zinc- The following is a study showing Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973827/pdf/ppat.1001176.pdf">https://www.ncbi.nlm.nih.gov/pmc/artic...
40. Here is a trial on the efficacy of Zinc on the common cold: https://www.ncbi.nlm.nih.gov/pubmed/15496046 ">https://www.ncbi.nlm.nih.gov/pubmed/15...
41. More studies on Zinc’s anti viral properties:
A) https://www.ncbi.nlm.nih.gov/pubmed/17344507 
B)">https://www.ncbi.nlm.nih.gov/pubmed/17... https://www.ncbi.nlm.nih.gov/pubmed/16982486 
C)">https://www.ncbi.nlm.nih.gov/pubmed/16... https://www.ncbi.nlm.nih.gov/pubmed/23775705 
D)">https://www.ncbi.nlm.nih.gov/pubmed/23... https://www.ncbi.nlm.nih.gov/pubmed/19341987 
E)">https://www.ncbi.nlm.nih.gov/pubmed/19... https://www.ncbi.nlm.nih.gov/pubmed/15189121 
F)">https://www.ncbi.nlm.nih.gov/pubmed/15... https://www.ncbi.nlm.nih.gov/pubmed/18279051 
G)">https://www.ncbi.nlm.nih.gov/pubmed/18... https://www.ncbi.nlm.nih.gov/pubmed/19906491 ">https://www.ncbi.nlm.nih.gov/pubmed/19...
43. 3) Another reason why Quercetin may be effective at combatting COVID19 is due to the fact that it may inhibit the cytokine storm induced by the coronavirus: #sec3-molecules-21-00450title">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273652/ #sec3-molecules-21-00450title">https://www.ncbi.nlm.nih.gov/pmc/artic...
44. 4) Another potential Quercetin anti-Covid-19 mechanism: https://mobile.twitter.com/taitlog/status/1248776042291933186">https://mobile.twitter.com/taitlog/s...
45. See this tweet as well: https://insight.jci.org/articles/view/125851">https://insight.jci.org/articles/... https://mobile.twitter.com/gstanchev/status/1249793675401375745">https://mobile.twitter.com/gstanchev...
46. And this tweet: https://mobile.twitter.com/__ice9/status/1249820862745894913">https://mobile.twitter.com/__ice9/st...
47. I will now proceed to link articles and videos related to Quercetin’s potential to fight COVID-19.
54. Quercetin as Zinc Ionophore and COVID-19 Outpatient Management By DrBeen Medical Lectures: https://m.youtube.com/watch?v=W9YFXo84lCk">https://m.youtube.com/watch...
55. MedCram Video Update #35- This was one of the first mentions on the potential of Quercetin to act as a Zinc Ionophore like Hydroxychloroquine to inhibit virus replication, thereby potentially acting as a treatment for SARS-COV-2/ COVID-19: https://m.youtube.com/watch?v=vE4_LsftNKM">https://m.youtube.com/watch...
56. Eastern Virginia Medical School Critical Care COVID-19 Management Protocol & earlier treatment recommendation/ They recommend Quercetin 250mg-500mg each day.
https://www.evms.edu/media/evms_public/departments/internal_medicine/EVMS_Critical_Care_COVID-19_Protocol.pdf">https://www.evms.edu/media/evm...
57. It also part of the daily regimen by Harvard Researcher, David Sinclair. https://blog.daveasprey.com/wp-content/uploads/2020/03/How-Harvard-Researcher-David-Sinclair-and-Dave-Asprey-Manage-COVID-19-Risk-–-681.pdf">https://blog.daveasprey.com/wp-conten...
58. I will now proceed to provide anecdotal evidence of people who took Quercetin/Zinc as a remedy for COVID-19. Thank you @ScarofOdysseusfor collecting many of these cases and your ongoing work on providing anecdotal support to this potential treatment. https://mobile.twitter.com/ScarofOdysseus/status/1249647539684552704">https://mobile.twitter.com/ScarofOdy...
59. https://mobile.twitter.com/ne02012/status/1248616751744421891">https://mobile.twitter.com/ne02012/s...
60. https://mobile.twitter.com/mozandy/status/1248384348367151106
https://mobile.twitter.com/mozandy/s... href=" https://mobile.twitter.com/mozandy/status/1248119917372637191">https://mobile.twitter.com/mozandy/s... https://mobile.twitter.com/mozandy/status/1249351313122627585">https://mobile.twitter.com/mozandy/s...
61. https://mobile.twitter.com/freedom9230/status/1249364687860436992">https://mobile.twitter.com/freedom92...
62. https://mobile.twitter.com/deNutrients/status/1247517665431900165">https://mobile.twitter.com/deNutrien...
63. https://twitter.com/ElissaBeth/status/1249918293420298241">https://twitter.com/ElissaBet...
64. https://mobile.twitter.com/Dota2funny1/status/1249484880049823749">https://mobile.twitter.com/Dota2funn...
65. https://mobile.twitter.com/rippingpants/status/1249509286067220480">https://mobile.twitter.com/rippingpa...
66. https://mobile.twitter.com/dgk3lly/status/1248757765582909440">https://mobile.twitter.com/dgk3lly/s...
67. https://mobile.twitter.com/MontyBestUK/status/1241412567039442944">https://mobile.twitter.com/MontyBest...
68. https://mobile.twitter.com/NordNights/status/1248259018730192896">https://mobile.twitter.com/NordNight...
69. https://mobile.twitter.com/SilverB79910844/status/1248065467241111552">https://mobile.twitter.com/SilverB79...
70. https://mobile.twitter.com/12gourmetfoodie/status/1247935774097580033">https://mobile.twitter.com/12gourmet...
71. https://mobile.twitter.com/AliasGrace6/status/1247612630845571072">https://mobile.twitter.com/AliasGrac...
72. https://mobile.twitter.com/aperfectstrange/status/1244985843057598466">https://mobile.twitter.com/aperfects...
73. https://mobile.twitter.com/dgk3lly/status/1247421469576941568">https://mobile.twitter.com/dgk3lly/s...
74. https://mobile.twitter.com/otc_chris/status/1247546483743784961">https://mobile.twitter.com/otc_chris...
75. https://mobile.twitter.com/ScarofOdysseus/status/1247501036815896576">https://mobile.twitter.com/ScarofOdy...
76. https://mobile.twitter.com/ErnieHoffmeist1/status/1247497772716003328">https://mobile.twitter.com/ErnieHoff...
77. https://mobile.twitter.com/Di8082/status/1247406492216524801">https://mobile.twitter.com/Di8082/st...
78. https://mobile.twitter.com/jackiescoones/status/1249792860158902273">https://mobile.twitter.com/jackiesco...
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