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Nigerians have questions about why it appears the #COVIDー19 virus is not as "serious" like reports from Italy, Spain et al. I have read a number of Scientific research papers exploring this. Yesterday I saw a tweet by @urchilla01 and I immediately wanted a Debate.
#MLS4COVID19
#MLS4COVID19
Apologies to @davidapaflo - I hope I got this right? My sin? Poaching your graphic for common good.
We want to explore why case fatalities for #COVIDー19 is "low" in Nigeria.
There are a number of hypotheses and @Idris_ArRazi has a paper awaiting review. #MLS4COVID19
We want to explore why case fatalities for #COVIDー19 is "low" in Nigeria.
There are a number of hypotheses and @Idris_ArRazi has a paper awaiting review. #MLS4COVID19
Also, @urchilla01 hypothesised that Corona virus was probably in Nigeria by December based on laboratory data - an increase in requests for throat swabs? & observation of an increase in respiratory issues by patients reporting in the hospital. This raises questions.
#MLS4COVID19
#MLS4COVID19
Has the number of requests for throat swabs and the number of patients presenting with respiratory issues in December 2019 been compared with previous December data for at least 5 - 10 years?
Any significant differences?
#MLS4COVID19
Any significant differences?
#MLS4COVID19
Also, Nigeria& #39;s weather type in December is usually harmattan. Do harmattan periods lead to an increase in respiratory issues?
Without appropriate tests, can we comfortably say a cough = #COVIDー19?
What does the research say about weather and severity of cases?
#MLS4COVID19
Without appropriate tests, can we comfortably say a cough = #COVIDー19?
What does the research say about weather and severity of cases?
#MLS4COVID19
Are there other factors that may explain seemingly low virulence observed in the almost 300 confirmed cases as reported by @NCDCgov
Or is the low virulence & low numbers a false appearance caused by low reporting and low testing?
How do we get the answer to this?
#MLS4COVID19
Or is the low virulence & low numbers a false appearance caused by low reporting and low testing?
How do we get the answer to this?
#MLS4COVID19
Is there an increase in unexplained deaths?
Who can compare the death rates dating back years to see if there is a surge in 2020 that could be due to unreported #COVIDー19 cases?
#MLS4COVID19
Who can compare the death rates dating back years to see if there is a surge in 2020 that could be due to unreported #COVIDー19 cases?
#MLS4COVID19
I will share the draft paper by @Idris_ArRazi at the end of this thread. But will share some excerpts here.
Link to full paper will be shared at the end of the thread.
#MLS4COVID19
Below are the summary facts from the paper:
Link to full paper will be shared at the end of the thread.
#MLS4COVID19
Below are the summary facts from the paper:
1. There appears to be disproportionate Case Fatalities Rate (CFR) across the world.
Deaths due to COVID-19 has not been the same e.g. Italy has higher death rates which some suggest is due to the higher ratio of the elderly in Italy compared with young.
#MLS4COVID19
Deaths due to COVID-19 has not been the same e.g. Italy has higher death rates which some suggest is due to the higher ratio of the elderly in Italy compared with young.
#MLS4COVID19
But the young also die. Some suggest this is due to previous history of immune - deficiency, altered respiratory function ailments like Asthma, cardiovascular issues etc
So what exactly determines severity of a #COVIDー19 infection? Remember , the Asymptomatic...
#MLS4COVID19
So what exactly determines severity of a #COVIDー19 infection? Remember , the Asymptomatic...
#MLS4COVID19
Science will always try to find the answers to many puzzling questions.
Some of the answers to the questions I have asked are already known.
So, I hope Medical Scientists will come on this thread to give clearer answers.
#MLS4COVID19
Some of the answers to the questions I have asked are already known.
So, I hope Medical Scientists will come on this thread to give clearer answers.
#MLS4COVID19
@Idris_ArRazi draft paper says the genetic makeup and stability of the Sars-CoV2 virus are key determinants that contribute to it& #39;s virulence and pathogenicity .
Does this mean viruses change in makeup and do not remain in one stable form. Are there variants?
#MLS4COVID19
Does this mean viruses change in makeup and do not remain in one stable form. Are there variants?
#MLS4COVID19
Another excerpt - "the S-glycoprotein is key because of it& #39;s role in host cells attachment (...) and pathogenicity of #COVIDー19
Implying?
The Sars-CoV2 virus molecular structure has protein components, one of which is S- glycoprotein that help it attach to cells
#MLS4COVID19
Implying?
The Sars-CoV2 virus molecular structure has protein components, one of which is S- glycoprotein that help it attach to cells
#MLS4COVID19
The S-Protein appears to change in the structure of virus seen from different patients and this mutation is suggested as a reason why the virulence is different in some populations.
Comparisons of the Nigerian viral genome structure may then give us more answers?
#MLS4COVID19
Comparisons of the Nigerian viral genome structure may then give us more answers?
#MLS4COVID19
For the draft paper and more scientific explanations, please read at http://bit.ly/mls4covid19
Now,">https://bit.ly/mls4covid... over to the experts, please review. The information above, do you agree or disagree with it?
What other reasons do you suggest is responsible for low cases in Africa
#MLS4COVID19
Now,">https://bit.ly/mls4covid... over to the experts, please review. The information above, do you agree or disagree with it?
What other reasons do you suggest is responsible for low cases in Africa
#MLS4COVID19
